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ARACHIDONATE 5-LIPOXYGENASE
Descriptors Found:
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DeCS
Descriptor
English
:
Arachidonate 5-Lipoxygenase
Descriptor
Spanish
:
Araquidonato 5-Lipooxigenasa
Descriptor
Portuguese
:
Araquidonato 5-Lipoxigenase
Synonyms
English
:
5-Lipoxygenase
Tree Number:
D08.811.682.690.416.583.500.055
D12.776.556.579.374.568.500.020
Definition
English
:
An enzyme that catalyzes the
oxidation
of
arachidonic acid
to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a
peroxidase
to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in
leukocytes.
Entry Combination - descr/qualif
English
:
Arachidonate 5-Lipoxygenase
/
antagonists & inhibitors
use
Lipoxygenase Inhibitors
History Note
English
:
91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
19074
Unique Identifier:
D001094
Occurrence in VHL
:
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DeCS
CID-10
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